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A 16-residue mitochondrial-derived peptide for metabolic and cellular-stress research.
MOTS-c is a 16-amino-acid peptide encoded within a short open reading frame of the mitochondrial 12S rRNA region. Its sequence is MRWQEMGYIFYPRKLR.
Cell and animal studies investigate mitochondrial-to-nuclear signalling, the folate-AICAR-AMPK pathway, metabolic homeostasis and stress-response gene expression. Effects can be model- and context-dependent, and the research does not establish suitability for human use.
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Compound identifiers describe the named reference molecule. The actual vial must always be checked against its label, certificate and safety documentation.
MOTS-c is a 16-amino-acid peptide encoded within a short open reading frame of the mitochondrial 12S rRNA region. Its sequence is MRWQEMGYIFYPRKLR.
Cell and animal studies investigate mitochondrial-to-nuclear signalling, the folate-AICAR-AMPK pathway, metabolic homeostasis and stress-response gene expression. Effects can be model- and context-dependent, and the research does not establish suitability for human use.
The strongest mechanistic evidence is preclinical; findings vary by model, cell type and experimental setting.
Registry values can differ by salt, counter-ion, hydrate, charge state or supplier representation. The lot certificate takes precedence.
Keep the sealed lyophilised material dry, protected from light and tightly closed.
For longer-term laboratory storage, -20°C is a commonly used condition for peptide reference materials; short-term requirements vary by sequence and formulation.
After preparing a laboratory solution, minimise time at room temperature and repeated freeze-thaw cycles. The lot-specific label, CoA and SDS take priority over general guidance.
No purity, origin or third-party-testing figure is claimed until Auren has a verified report for the specific released lot.
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