TB-500

TB-500 is commonly used for the acetylated thymosin beta-4 fragment Ac-LKKTETQ, corresponding to residues 17-23 of the parent protein. The name is sometimes used inconsistently for other thymosin beta-4 materials, so sequence confirmation on the lot-specific certificate is essential.

The LKKTETQ region has been examined in biochemical and cell models involving actin binding, cytoskeletal organisation and cell migration. Findings for the fragment should not be automatically attributed to full-length thymosin beta-4, or vice versa.

Sequence

Ac-LKKTETQ

Molecular formula

C38H68N10O14

Molecular weight

889.0 g/mol

PubChem CID

62707662

Parent protein region

Thymosin beta-4 residues 17-23

Form

Lyophilised powder

Registry values can differ by salt, counter-ion, hydrate, charge state or supplier representation. The lot certificate takes precedence.

1. 01

   Keep the sealed lyophilised material dry, protected from light and tightly closed.

2. 02

   For longer-term laboratory storage, -20°C is a commonly used condition for peptide reference materials; short-term requirements vary by sequence and formulation.

3. 03

   After preparing a laboratory solution, minimise time at room temperature and repeated freeze-thaw cycles. The lot-specific label, CoA and SDS take priority over general guidance.