TESAMORELIN

Tesamorelin, also known as TH9507, is a synthetic 44-amino-acid analogue of human growth-hormone-releasing hormone. An N-terminal trans-3-hexenoyl modification distinguishes it from native GHRH and improves resistance to N-terminal enzymatic cleavage.

Laboratory work examines GHRH-receptor binding, Gs/cAMP signalling and downstream GH-axis pathways. Salt and counter-ion forms can change the reported formula and mass, so the free-peptide identifiers below must be reconciled with the batch certificate.

Synonym

TH9507

Molecular formula

C221H366N72O67S

Molecular weight

5135.9 g/mol

CAS number

218949-48-5

PubChem CID

16137828

Form

Lyophilised powder

Registry values can differ by salt, counter-ion, hydrate, charge state or supplier representation. The lot certificate takes precedence.

1. 01

   Keep the sealed lyophilised material dry, protected from light and tightly closed.

2. 02

   For longer-term laboratory storage, -20°C is a commonly used condition for peptide reference materials; short-term requirements vary by sequence and formulation.

3. 03

   After preparing a laboratory solution, minimise time at room temperature and repeated freeze-thaw cycles. The lot-specific label, CoA and SDS take priority over general guidance.